Buy T3 30mcg by Adelphi Research Laboratory
History of T3 (T-3):
Liothyronine is a thyroid hormone T3 that is generally produced in a 4:1 ratio by the thyroid gland as compared to T4:T3. Liothyronine is the active form of thyroxine, which is made up of tyrosine and bonded iodine in a basic chemical structure. King Pharmaceuticals created the exogenous liothyronine product, which was approved by the FDA in 1956.
Chemical Formula of T3 (T-3):
Indication of T3 (T-3):
The following uses of liothyronine have been approved by the FDA:
- Replacement therapy for congenital or acquired hypothyroidism, whether primary (thyroidal), secondary (pituitary) or tertiary (hypothalamic).
- In the treatment of thyroid cancer, as a supplement to surgery and radioiodine.
- As a diagnostic agent in thyroid gland autonomy or mild hyperthyroidism suppression tests.
Exogenous liothyronine is used to restore T3 plasma levels and replace inadequate hormonal synthesis. A deficiency of liothyronine can manifest as a pale, bloated face, coarse, brittle hair, dry skin, croaky voice, constipation, irregular periods, drowsiness, and lethargy, as well as irregular periods, drowsiness, and lethargy.
Mechanism of action of T3 (T-3):
Endogenous thyroid hormone is replaced by liothyronine, which subsequently exerts its physiologic effects through influencing DNA transcription and protein synthesis. The binding of liothyronine to thyroid receptors linked to DNA produces this action on DNA. The effects of exogenous liothyronine are identical to those of endogenous thyroid T3 hormone.
As a result, it raises energy expenditure, accelerates cellular oxidation, stimulates body tissue growth, maturation, and metabolism supports nerve myelination and synaptic process development in the nervous system and improves carbohydrate and protein metabolism.
Thyroid hormones, T4 and T3, enter cells via both passive and active processes. T3 in the cell cytoplasm and T3 produced by T4 within the cell diffuse into the nucleus and bind to thyroid receptor proteins that appear to be predominantly linked to DNA. Receptor binding causes DNA transcription to be activated or repressed, affecting the quantity of mRNA and the proteins that follow. Protein concentration variations are responsible for the metabolic alterations seen in organs and tissues.
Anticoagulants used orally:
Thyroid hormones appear to promote the breakdown of vitamin K-dependent clotting components. When oral anticoagulants are used, compensatory improvements in clotting factor production are inhibited.
Insulin or oral hypoglycemics: Starting hormone therapy medication may increase insulin or oral hypoglycemic needs.
Cholestyramine binds to both T4 and T3 in the gut, limiting thyroid hormone absorption. As a result, 4 to 5 hours should pass between cholestyramine and thyroid hormone delivery.
Thyroid hormone formulations are typically contraindicated in individuals who have been diagnosed but have not yet been treated for adrenal cortex insufficiency, unresolved thyrotoxicosis, or an obvious allergy to any of its active or extraneous elements.
How to use T3 (T-3):
On an empty stomach, take tablets with a full glass of water 30 minutes to 1 hour before breakfast. When taking levothyroxine, avoid foods that reduce absorption (soybean products).
Side effects of T3 (T-3):
Cytomel has the potential to induce major adverse effects, such as:
- trouble sleeping,
- increased sweating
Keep this drug away from heat, moisture, and light at 68°F to 77°F (20°C to 25°C). Keep any medications out of children’s reach. After the expiration date, throw away any unused medicine. Do not dump or spill unused drugs down the sink or drain.