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LETROZOLE 2.5MG

£35.00

LETROZOLE 2.5MG

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UK PHARMACEUTICAL GRADE

NAME Tamoxifen  
MG 2.5 MG
AMOUNT 28 TABLETS

20 in stock

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Description

Buy LETROZOLE 2.5 MG
Buy LETROZOLE 2.5 MG

Buy LETROZOLE 2.5 MG

History of LETROZOLE 2.5 MG:

Letrozole, also known as CGS 20267, is a nonsteroidal type II aromatase inhibitor that was originally identified in the literature in 1990. It is a third-generation aromatase inhibitor, like exemestane and anastrozole, which means it does not affect cortisol, aldosterone, or thyroxine levels.

Chemical Formula of LETROZOLE 2.5 MG:       

C17H11N5

Indication of LETROZOLE 2.5 MG:

Letrozole is approved for the treatment of postmenopausal women with hormone receptor (HR) positive early breast cancer, postmenopausal women with early breast cancer who have already had tamoxifen treatment, and postmenopausal women with HR+ or unknown advanced breast cancer.

Letrozole, in combination with ribociclib, is indicated for the treatment of premenopausal, perimenopausal, and postmenopausal women with HR+ and HER2 negative advanced or metastatic breast cancer.

Mechanism of action of LETROZOLE 2.5 MG:

Letrozole is a non-steroidal aromatase inhibitor of type II. It obstructs the active site of CYP19A1 and hence the electron transfer chain. This competitive inhibition inhibits androgens from being converted to oestrogen. This action results in a decrease in uterine weight and an increase in luteinizing hormone. In postmenopausal women, the action of aromatase is responsible for the majority of oestrogen production. With the reduced availability of oestrogen, estrogen-dependent cancers regress.8 Third generation aromatase inhibitors do not significantly alter cortisol, aldosterone, and thyroxine levels

How to use LETROZOLE 2.5 MG:

Letrozole suggested dose is one 2.5 mg tablet taken once a day, without regard for food. Take the medication exactly as directed by your primary care physician. While ingesting the tablet, drink a glass of water.

Precautions

Before using letrozole, notify your doctor or pharmacist if you are allergic to it, anastrozole, or any other medications. Inactive chemicals in this product may trigger a reaction or other complications. For further information, see your pharmacist.

Tell your doctor or pharmacist about your medical history, especially if you have: increased blood fats, bone issues, stroke or blood clots, cardiovascular disease, hypertension, renal difficulties, or liver failure.

Interactions

Drug interactions can cause your medicines to malfunction or put you at risk for harmful side effects. This list does not cover every possible pharmaceutical interaction. Keep a note of everything you use and talk to your doctor and pharmacist about it. Do not begin, discontinue, or change the dose of any drugs without first talking with your doctor.

When both medicines are used simultaneously, tamoxifen lowers blood levels of letrozole. However, in clinical trials, the effectiveness of letrozole was not diminished when given shortly after tamoxifen. Letrozole is an anti-estrogen medication. As a result, estrogen-containing products work to offset the effects of letrozole.

Benefits:

After menopause, this medicine is used to treat some forms of breast cancer in women. Letrozole is also used to assist prevent cancer recurrence. A natural hormone called oestrogen stimulates the growth of certain breast tumours. Letrozole reduces the amount of oestrogen produced by the body, which aids in the slowing or reversal of the progression of certain breast cancers.

Side effects:

side effects of letrozole include:

  • headaches, nausea, and vomiting.
  • change of appetite.
  • constipation.
  • carpal tunnel syndrome.
  • hair and skin changes.
  • vaginal bleeding.

Storage:  

Keep this drug away from heat, moisture, and light at 68°F to 77°F (20°C to 25°C). Keep any medications out of children’s reach. After the expiration date, throw away any unused medicine. Do not dump or spill unused drugs down the sink or drain.

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External Links

Buy LETROZOLE and get detail on usada.org

Buy LETROZOLE and get detail

Buy Letrozole 2.5 mg film-coated Tablets

 

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